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Curcumin: positive results in bone health support

Milan, May 22nd, 2017 – A new pilot human study[1] reveals that a curcumin-based supplementation may be helpful in maintaining at a healthy level bone density.[2]  This study, the first one conducted in humans with curcumin-based product, further evaluates the efficacy and safety of Indena’s bioavailable Phytosome® formulation of curcumin, Meriva®, in asymptomatic subjects with a bone density condition. Meriva_2015

The study enrolled 57 healthy subjects with a bone mass condition, randomized in two different groups, comparable in terms of age and gender. During the 6-month experimental period, the control group followed a standard management (SM) to control the bone density; the supplement group combined the SM with a daily curcumin-based oral supplementation consisting of 1g of Meriva®. Remarkable results have been observed in the Meriva® supplemented group, reaching at the end of the study (week 24) +7.1% and +4.8% levels of bone density of the small finger and upper jaw, paralleled with a 21% decrease of ultrasound transmission values. No significant changes were observed in the control group.

Antonella Riva, Product Research Manager at Indena, commented: “These new positive clinical data broaden the existing findings on the efficacy of dietary supplementation with Meriva® in contributing to manage certain health conditions, potentially impacting on life quality, including bone health.”

“We are very proud to add this new evidence to the science supporting Meriva®. It is a promise being delivered by Indena to its Partners and Consumers” – added Cosimo Palumbo, Indena Marketing Director “Meriva® continues to lead modern, rigorous clinical development in the turmeric space. More studies are on-going and we will soon hear again about the benefits connected with the use of our unique, food grade, highly tolerable formulation of curcuminoids.”



[1] – Dugall M, et al, Effects of a curcumin-based supplementation in asymptomatic subjects with low bone density: a preliminary 24-week supplement study. European Review for Medical and Pharmacological Sciences 2017; 21: 1684:1689.

[2] – Buencamino MC, Sikon AL, Jain A, Thacker HL, An observational study on the adherence to treatment guidelines of osteopenia. J Womens Health (Larchmt) 2009; 18: 873:881.


Meriva® is a patented delivery form of curcumin based on Indena’s proprietary Phytosome® technology, for healthy inflammatory response, joint health and eye health. Pharmacokinetic comparison studies have shown Meriva® to improve the overall curcuminoids bioavailability by about 30-fold, and significant absorption benefits; in particular, demethoxycurcumin (the most potent curcuminoid in numerous bioassays) was found to be 50-fold more bioavailable as compared to a non-formulated curcumin extract. Indena technology relies on the use of dietary adjuvants (lecithin) and is supported by 29 clinical trials on efficacy and by a robust tolerability and safety profile.

Further info on Meriva® and other Phytosomes: www.phytosomes.info

To know more about Phytosome® technology watch the videoPhytosome®: The technology explainedon the Indena YouTube channel


Indena Press Contacts:

Cohn & Wolfe Milan
Laura Faravelli: laura.faravelli@cohnwolfe.com
Lorenzo Petracco: lorenzo.petracco@cohnwolfe.com
Tel. +39 02 202391


Please note that the physiological activity of the ingredient described herein is supported by the referenced clinical trial reports. Marketers of finished products containing the ingredient described herein are responsible for determining whether the claims made for such products are lawful and in compliance with the laws of the country in which they will market the products.

These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.

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