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Sports nutrition: Meriva® wins against osteo-muscular discomfort conditions

A pilot study confirms the high tolerability of Meriva®, when compared to the best standard management

Milan, February 7th, 2018 – A new pilot human study [1] confirms that supplementation of Meriva®, the Indena’s proprietary lecithin-based and diet inspired delivery system of curcumin, may represent a promising, safe mean to preserve  osteo-muscular efficiency when performing intense, high impact, physical activities, exerting its beneficial effect even with a short term treatment.


The study enrolled 50 male rugby players with osteo-muscular discomfort due to repeated hard tackles, physical overload or acute episode of recurrent discomfort. They received a Meriva®-based product containing 2 grams of  curcumin Phytosome® (n=25, 1 tablet containing 1g of Meriva® every 12 hours) for 5 or 10 days or best standard management (n=25). The discomfort perception (estimated according to the visual analog scale devised by Scott-Huskinsson) and functio lesa (scored by an arbitrary scale ranging from complete physical function to maximum impairment of physical function) have been evaluated at baseline and after 1 (T1), 3 (T3), 6 (T6), 10 (T10) and 20 (T20) days from the start of the treatment.

The group supplemented with Meriva® showed an excellent adherence to treatment (24/25 subjects, 96%) compared to the group following the best standard management (15/25 subjects, 60%) (exploratory p-value = 0.005). Moreover, the tolerability was scored as excellent by 24 (96%) subjects who received Meriva®, and by 14 (56%) subjects treated with the best standard management (exploratory p-value = 0.002). Among participants supplemented with Meriva®, only 1 (4%) experienced mild side effects, and 4 (16%) subjects treated with the best standard management reported gastric pain as an adverse event.

Furthermore, even with short-term treatment, the group supplemented with Meriva® showed improvement on impaired physical functions and on the feeling of physical discomfort.

Intense, high impact, physical activities are often associated with osteo-muscular conditions. Meriva®, even when administered at higher dosages, has been determined to be a safe and tolerable agent that could avoid the common gastric side effects associated with the use of many anti-inflammatory remedies that are the best standard management – commented Antonella Riva, Product Research Manager at Indena.

“Meriva® is a best case of how modern science and ancient wisdom can lead to outstanding results. Our customers can count on our ongoing commitment in obtaining the best standardized extracts, whose safety and efficacy are scientifically proven by broad-based documentation. The science behind Meriva® and Phytosome® technology allows Indena and its customers to capitalize the health benefit of turmeric, going way beyond its poor bioavailability – added Cosimo Palumbo, Indena Marketing Director.



[1] – Scaltrini S et al., , Eur Rev Med Pharmacol Sci, 2017; 21: 4935-4940.


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Please note that the physiological activity of the ingredient described herein is supported by the referenced clinical trial reports. Marketers of finished products containing the ingredient described herein are responsible for determining whether the claims made for such products are lawful and in compliance with the laws of the country in which they will market the products.
These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.

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