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Vazguard<sup><sup>®</sup></sup>
Vazguard<sup><sup>®</sup></sup>

NUTRACEUTICALS

Vazguard®

Bergamot - Indena Phytosome™

THE SHIELD AGAINST VISCERAL FAT

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Overview

We’ve set the absolute advantage

Citrus bergamia Risso et Poiteau, the scientific name of Bergamot, has been endemic in the Mediterranean area for several centuries and currently its production is limited to the Calabria region (Southern Italy) where is traditionally considered as "the King of citrus fruits".

Vazguard® is a standardized extract from Bergamot with Indena Phytosome™ formulation to enhance the power of its components.

It has shown to provide support in case of challenges related to metabolic health – sustained by inner abdominal fat, high blood sugar, fatty liver, and abnormal cholesterol or triglyceride levels.
These conditions are commonly associated with lack of physical activity, overweight, unbalanced diet, and irregular lifestyle, making Vazguard® a valuable metabolic balance companion.

Moreover, its beneficial properties are able to support healthy metabolic key parameters even in individuals undergoing pharmacological therapies based on GLP-1 agonists.

We’ve set the absolute advantage

Vazguard® into action

Vazguard® is effective thanks to the power of its unique mix of polyphenols enhanced by Indena PhytosomeTM proprietary technology: in particular, flavonoids – found in bergamot – are responsible for its higher antioxidant power compared to other plants from the Citrus genus.
Notably, Vazguard® shares the same phytochemical profile as bergamot juice, a common edible fruit.1

Specifically, Vazguard® is effective in supporting healthy blood levels through the optimization of total cholesterol, LDL, HDL, triglycerides, and glucose levels.2
All of this is achieved with just 500 mg twice a day – the same amount of polyphenols found in about a glass of bergamot juice.1

Vazguard® is the first bergamot ingredient with a scientifically demonstrated beneficial effects on human gut microbiota as proven in an ex-vivo study.3

A very recent pre-clinical investigation has proven Vazguard® to act as a GLP-1 modulator, validating its potential role as a companion ingredient for subjects undergoing pharmacologic treatments.4

Vazguard<sup>®</sup> into action

Find out how Vazguard®
is one step beyond

Vazguard® effectiveness relies in the raw material origin and in the fine extraction process.

In the production of Vazguard®, only Bergamot from a very small and specific part of the southern Italian region Calabria is used and its phytochemical composition is extensively characterized to make Vazguard® retain the same, unique phytochemical profile of the natural bergamot juice. Plus, one of its components - bergamjuicin - has been discovered and isolated by Indena.

And, there’s more: the uniqueness of Vazguard® deeply lies in its Indena Phytosome™ strategy, a delivery system that optimizes the biological absorption of polyphenols, which are normally poorly soluble in both water and organic solvents.

Find out more on Indena Phytosome™

Things to Watch

Things to watch

Vazguard® 
The shield against visceral fat

Have you ever heard about a type of fat called visceral or intra-abdominal fat? It can be dangerous for your health and no specific medication can keep it at bay. Find out all the beneficial properties of Vazguard®, the natural ingredient derived from Citrus bergamia.

PRODUCTS / 24 Apr 25
3.34
Vazguard<sup>® </sup><br /><strong><em>The shield against visceral fat</em></strong>
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See through science

Bibliography
1Formisano C. et al,J. Agric. Food Chem. 67, 3159−3167 (2019).
2Rondanelli M. et al., Phytotherapy Res, (2020).
3Riva A. et al., J Appl.Microb Res., 3 (2), 45-51 (2020).
4Indena data on file, manuscript in preparation.

VAZGUARD® at a glance

Why choose Vazguard®?

01.

Is based on a natural and food-grade delivery system Indena Phytosome™ to optimize the biological absorption of polyphenols, which are normally characterized by poor solubility in both water and organic solvents.

02.

Is derived from Citrus bergamia, exclusively sourced from a specific part of Southern Italy to guarantee the ingredient quality.

03.

Retains the same, unique phytochemical profile as natural bergamot juice: its standardization in guaiacyl bioflavonoids, is unique to Italian bergamot that outperforms all others Citrus flavonoids as antioxidants.

04.

Is extremely effective in supporting health in case of challenges related to metabolic syndrome - sustained by inner abdominal fat - like high blood sugar, fatty liver, abnormal cholesterol or triglyceride levels, commonly associated to lack of physical activity, overweight, unhealthy diet and irregular life-style.

05.

Is a multi-target ingredientIts, and benefits can be measured in only 30 days.

06.

Is the only bergamot ingredient with a scientific demonstration of activity on gut microflora.

07.

Is made in Italy through a highly controlled and sustainable supply chain.

08.

Is supported by a solid technical documentation package. Indena’s customer support is available to customers for any detail on product quality, safety, activity and human study information.

Technical Data

Common Name

Bergamot phoshpolipids

Botanical Origin

Citrus bergamia Risso & Poit.

Type

Extract

Plant source

Fruit juice

Health benefit

Cardiovascular Health, Healthy blood levels, Metabolism balance

Patent & Trademark

Vazguard is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject to Indena’s authorization.

Specifications

Standardized to contain 14-18% of total bergamot flavanones

Recommended dose and use

500 mg twice a day. Vazguard® is a light-yellow powder for use in nutritional supplement formulations.

Assay

>14% <18% of total flavanols by LC

Broad category

Weight loss companions

These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.

VAZGUARD® documents

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