PURIFICATION, THE SOURCE OF HEALTH
Browse all Indena’s documents about products, events, company information and so much more.
Go to section
NUTRACEUTICALS
Purebkale®
Brassica oleracea seed extract
Scroll to see more
Overview
We’ve set the absolute advantage
Brassica oleracea – a green leafy plant that has been cultivated as a food crop since 2000 BC – is a prominent member of the Brassicaceae botanical family, which has been gaining popularity for its widely studied health benefits.
But did you know that its seeds, in addition to its leaves, are packed with molecules that offer precious nutrients to our body? In particular, Brassica oleracea seeds are a valuable source of glucoraphanin, a compound that the myrosinase activity – by specific bacteria of our gut microbiota – metabolizes into sulforaphane (SFN). SFN is an active isothiocyanate with powerful antioxidant properties, which plays a key role in the detoxification and protection of numerous organs, including the skin and the liver.1
That’s why we’ve developed Purebkale®: an innovative nutraceutical based on an aqueous dry extract of exclusively 100% Italian Brassica oleracea seeds, which guarantees high levels of glucoraphanin (≥17%) to maximize SFN’s significant beneficial effect to support natural detoxification and purification processes.
Boosting the body’s antioxidant defenses and improving cellular resilience, Purebkale® helps protect the skin against oxidative stress, in favor of a smoother and more radiant appearance . Harnessing the power of carefully selected botanical sources and supported by advanced research, Purebkale® represents a new frontier in beauty-from-within solutions, where science meets nature to support youthful, healthy-looking aging journey.
Purebkale® into action
Both in vitro and in vivo studies have explored Brassicaceae multi-faceted approach to detoxifying the body. With these premises, a comprehensive phytochemical characterization on Purebkale® has been performed, demonstrating how the ingredient preserves the full phytocomplex of the natural biomass, including flavonoids, oxidoreductase enzymes (e.g., NADP) with sulforaphane-like biological activity, and residual endogenous myrosinase, potentially enhancing sulforaphane formation.2
Preclinical studies conducted on fibroblast cell lines exposed to pollutants demonstrated that Purebkale® exerts strong antioxidant effects, positively modulates inflammatory responses, and enhances cellular defence mechanisms against external stressors. In particular, the protective activity was observed against particulate matter (DPE), a major contributor to environmental pollution known to accelerate skin aging processes and promote inflammatory or allergic skin conditions, including atopic discomforts.2
Purebkale® efficacy in favour of skin health is proven also in human. A clinical open-label study involving 56 healthy female subjects, showed Purebkale® benefits on skin architecture, density, and functional quality.
Purebkale® was proven effective in restoring multiple markers of ageing, including barrier integrity and dermis structure, with the first results reported after only 28 days of supplementation. These outcomes were assessed through advanced instrumental techniques, but also subjective self-evaluation questionnaires, with no adverse events recorded.3
Find out how Purebkale® is one step beyond
The distinguishing feature of Purebkale® as a nutraceutical lies in the excellent quality of its core primary ingredient. Right from the start, Indena conducted a thorough screening of over 20 seed samples from different varieties of kohlrabi and tuscan black kale, to identify the best blend.
This effort has allowed the development of an extract with a significantly high concentration of the SFN precursor glucoraphanin, standardized at a minimum concentration of 17%, achieved without the use of solvents.
Indena also takes pride in Purebkale®’s Brassica oleracea seed supply chain, working in harmony with local communities to ensure an environmentally friendly production process.
Bibliography
1Cascajosa-Lira, Antonio, et al. Phytomedicine 130 (2024): 155731.
2Indena data on file
3Jahangiri Manesh, M.R., et al. Cosmetics. 13, 47. (2026
Thiings to watch
Things to watch
Beauty From Within
Find your inner health, and let it show.
What if beauty wasn’t just something you see, but something you feel? Find out how Indena is redefining the importance of looks through a holistic, science-backed approach that starts from within – thanks to targeted botanical ingredients that help nourish skin, hair, and nails by supporting the body’s internal balance.
HEALTH STORIES / 10 Jul 26
3.15
PUREBKALE® AT A GLANCE
Why choose Purebkale®?
01.
Purebkale® is a premium food-grade ingredient.
02.
Purebkale® is standardized by HPLC, containing a uniquely high concentration (≥17%) of glucoraphanin, precursor of SFN.
03.
Purebkale® preserves a high-quality phytochemical profile.
04.
Purebkale® shown, at cellular level, its important protective activities from environmental pollutants.
05.
Purebkale® is clinically tested to restore physiological skin parameters and has been found to be safe and well tolerated.
06.
Purebkale® is environmentally friendly, local production process of the Brassica oleracea seed ingredient.
HEALTH NEED
Beauty from within
The path to visible beauty lies beneath the surface: follow nature’s guide to nurture skin, hair, and overall vitality from the inside out. Our powerful botanical ingredients help reduce oxidative stress, slow the signs of aging, and support a glowing, resilient appearance – naturally.
HEALTH NEED
Healthy Aging
Average life expectancy continues to increase, yet aging remains a complex process: capabilities, looks and expectations change – and health strategies must adapt.
Our holistic approach leverages the power of natural ingredients to promote inner health, at the cellular and functional level, as well as a more youthful appearance. So everyone can live fully and age gracefully.
Technical data
Common Name
Brassica oleracea seed extract
Type
Extract
Plant source
Seed
HALAL Certified
Health benefit
Liver health, Skin health, Healthy appearance
Patent & Trademark
Purebkale is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject to Indena’s authorization.
Specifications
Purebkale® is standardized to contain ≥17% of glucoraphanin by HPLC.
Recommended dose and use
150 mg/day, providing 25 mg/day of sulforaphane glucosinolate. Purebkale™ is a dark brown powder for use in nutritional supplements.
Assay
≥17% of glucoraphanin by HPLC
Broad category
Beauty from within, Weight loss companions, Healthy Aging
These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.
PUREBKALE® DOCUMENTS
