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NUTRACEUTICALS
Ubiqsome®
CoQ10 - Indena Phytosome™
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Overview
We’ve set the absolute advantage
Coenzyme Q10 (CoQ10) is a compound naturally produced by the body, essential for cellular energy and known for its antioxidant properties. However, its endogenous production tends to decline due to several internal and external factors.
Ageing is a primary cause: as we get older, CoQ10 biosynthesis slows down, contributing to reduced energy levels and increased oxidative stress. Certain medications, especially statins, can also interfere with its production.
Intense or prolonged physical activity raises mitochondrial energy demands and can accelerate CoQ10 consumption, especially when synthesis is already compromised.
Additionally, chronic illness, unbalanced diet, and psychological stress—can further impair the body’s ability to maintain adequate CoQ10 levels.
Recognizing these factors is key to understanding when CoQ10 support may be beneficial, especially with age, medication use, or a demanding lifestyle.
Thanks to its original Indena Phytosome™ formulation, Ubiqsome® reaches the inner cellular space and – unlike any other supplements – can represent a valuable solution to help rebalance the body’s physiological production and demand for CoQ10.
Ubiqsome® into action
Ubiqsome® emerges as the real game-changer in the field of CoQ10-based ingredients: thanks to its proprietary Indena Phytosome™ technology and proven via various scientific evidences, it delivers coenzyme Q10 to the intended target muscle cells.
Improvement of coenzyme Q10 in muscle cells after Ubiqsome® supplementation was uniquely proven on healthy, aging runners, and further confirmed in ex-vivo and preclinical investigations.1-3
Ubiqsome® also ensures optimal CoQ10 plasma levels even after just one supplementation, and shows an evident dose-dependent trend after a mere 2 weeks of intake.4
Antioxidant power of CoQ10 enhanced in Ubiqsome® allows to support muscle function in several discomforts, including physical and sport distress, also favouring muscle health in case of long-term treatments (e.g. statins and GLP-1 agonists).
A human study showed Ubiqsome® has beneficial effects on elderly people with statin-related asthenia. What is the mechanism behind this evidence? Statins act by blocking the molecular pathway that leads to the synthesis of cholesterol, and in parallel also to the formation of CoQ10.5
Clinical evidence in healthy young adults shows that Ubiqsome® supplementation enhances endothelial function both acutely and over time, being endothelial function a key early indicator of cardiovascular health.6
Ubiqsome® is furthermore the valuable ally to nurture skin health from within: human evidence show its capacity to increase CoQ10 content in dermal fibroblasts after oral intake.2
Indena Phytosome™
Find out how Ubiqsome®
is one step beyond
Ubiqsome® is the only CoQ10 formulation to benefit from Indena Phytosome™ delivery system, a strategy that optimizes the bioabsorption of this important cofactor.1
Outstanding clinical results have been accomplished, thanks to the innovative Indena Phytosome™ technology platform, also in enhancing one of CoQ10’s limiting factors: oral bioavailability and muscle cells uptake. The coenzyme’s high molecular weight and its very low aqueous solubility usually make it unsuitable for the oral administration route: that’s where the Indena Phytosome™ delivery system is particularly useful, improving and optimizing the uptake for more refractory cells and tissues.
In addition, Ubiqsome® is the first CoQ10 formulation to have been tracked down to its real target, the inner space of cells where it is needed.
See through science
Peer-reviewed science on Ubiqsome®
Here you can find more scientific evidence for your review.
ACCESS NOWBIBLIOGRAPHY
1Drobnic F. et al., J Food Sci Nutr Res 3 (4):262-275 (2020).
2Marcheggiani F. et al., Antioxidants 12.4:964 (2023).
3Rizzardi N. et al., Antioxidants 0.6: 927 (2021).
4Petrangolini G, et al., Curr Drug Deliv.16(8):759-767 (2019).
5Fogacci F. et al., Journal of Clinical Medicine 13.13:3741 (2024).
6Cicero AFG. et al., Biofactors. Sep;48(5):1160-1165 (2022).
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Beauty From Within
Find your inner health, and let it show.
What if beauty wasn’t just something you see, but something you feel? Find out how Indena is redefining the importance of looks through a holistic, science-backed approach that starts from within – thanks to targeted botanical ingredients that help nourish skin, hair, and nails by supporting the body’s internal balance.
HEALTH STORIES / 21 May 25
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UBIQSOME® at a glance
Why choose Ubiqsome®?
01.
Ubiqsome® is the optimized delivery form of Coenzyme Q10, formulated with Indena Phytosome™ technology.
02.
Ubiqsome® is supported by single and repeated-dose pharmacokinetic studies, showing optimized CoQ10 plasma levels in a dose-dependent fashion and 14-fold higher solubility in simulated intestinal fluids.
03.
Ubiqsome® has a unique demonstration of CoQ10 muscle levels improvement in humans.
04.
Ubiqsome® optimizes CoQ10 levels in epithelial cells, thus supporting beauty from within.
05.
Ubiqsome® is the first and only CoQ10 formulation on the market to have been tracked from oral administration down to its single, real target: the inner space of cells.
06.
Ubiqsome® is clinical validated as support to the endothelial function’s ability to fight oxidation.
07.
Ubiqsome® favours muscle health in case of long-term medications including statin-related adverse effects.
08.
Ubiqsome® could be a promising ingredient for cardiovascular health, being able to protect from cardiovascular risk factors.
09.
Ubiqsome® can be a cost-effective solution thanks to optimized bioabsorption – allowing for lower CoQ10 content without relying upon expensive capsulating technologies, as well as industrial scalability and versatile finished oral dosage forms.
HEALTH NEED
Beauty from within
The path to visible beauty lies beneath the surface: follow nature’s guide to nurture skin, hair, and overall vitality from the inside out. Our powerful botanical ingredients help reduce oxidative stress, slow the signs of aging, and support a glowing, resilient appearance – naturally.
HEALTH NEED
Weight loss companions
GLP-1 agonists are reshaping weight management – but not without challenges. Our botanical ingredients are designed to accompany the weight loss journey before, during, and after treatment, helping to counter side effects and support metabolic balance.
Technical Data
Common Name
CoQ10 phospholipids
Type
Ingredient with optimized bioabsorption
Plant source
-
Health benefit
Anti-ageing, Cellular energy support, Physical strength and performance, Senolytic, Skin health
Patent & Trademark
Ubiqsome is patented (EP3307244).
Ubiqsome is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject to Indena’s authorization.
Specifications
Standardized to contain 18-22% of coenzyme Q10
Recommended dose and use
Up to 500 mg/day. Ubiqsome® may be used in a variety of supplement formulations.
Assay
18-22% of coenzyme Q10 by HPLC
Broad category
Weight loss companions, Beauty from within
These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.
UBIQSOME® documents
