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Quercefit<sup>®</sup>
Quercefit<sup>®</sup>

NUTRACEUTICALS

Quercefit®

Quercetin Phytosome™

HIT MULTIPLE TARGETS,
NATURALLY

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NEW SCIENTIFIC EVIDENCE

EYE HEALTH AND ALLERGY SYMPTOMS TWO ISSUES, ONE SOLUTION1,2

Science confirms it again: Quercefit® can be a reliable ally when viral infections may threaten our immune system. The concluding phase of a recent clinical study has shown that supplementing with quercetin Phytosome™ helps keep subjects’ immune system strong, providing quicker recovery and milder symptoms occurrence in the event of Sars-CoV-2 infection.2

Explore the results

Overview

We’ve set the absolute advantage

Quercetin is a natural flavonoid compound widely found in vegetables, fruits and nuts. Quercefit®, in particular, is derived from the flower buds of Sophora japonica L.3 and shows an activity profile that can be best described as “pleiotropic”, due to its beneficial effects on several and diverse physiological processes.3

For example, in-vitro, in-vivo and human studies have reported that quercetin – the queen of flavonoids – exhibits positive influence on blood circulation, immunity, virus exposure protection, metabolism and, more recently, eye health.3,4

At cellular level, quercetin shows:
Antioxidant activity, through the direct inactivation of free radicals, inhibition of lipid peroxidation and inhibition of free radicals producing enzymes.5
Modulation activity on the most important inflammatory cascades, leveling down NF-kB activation, controlling COX and LOX activation and cytokine production.5
Immunomodulation activity hampering histamine release, promoting IFN-γ release and fighting IgE.6

Quercefit® is your Ticket to Ride anywhere, at any time.

We’ve set the absolute advantage

Quercefit® into action

Thanks to its original formulation, Quercefit® can hit its targets with far more efficiency than unformulated quercetin. Indeed, it shows optimized bioabsorption and solubility, so it can be used at lower dosages retaining efficacy with no undesirable side effects.3
Let’s see how it works.

IMMUNITY HEALTH AND SENOLYTIC FUNCTION
Recent studies show that Quercefit® helps maintain immune system health and modulates cytokine cascade. Thus, it improves the conditions of those exposed to Covid-19, precisely thanks to its senolytic function: its supplementation helps people maintain healthy condition in a Sars-CoV-2 infectious environment. While the standard precautionary measures and treatments defined by medical protocols cannot be replaced, the severity of symptoms often depends on the way the initial phases of the illness are faced.7

This evidence has been confirmed by recent human studies that showed how Quercefit® can support the immune system, even in the presence of Covid-19 infection, in terms of virus clearance optimization and milder symptoms.1,2

Quercefit<sup>®</sup> into action

ALLERGIES
Quercefit® is a natural remedy during allergy season, promoting the wellbeing of sensitive and intolerant subjects in periods when allergens are abundant and widespread. A wish come true for all allergy-prone people.8
And its potential against allergies doesn’t end there: a recent study on mildly symptomatic individuals highlighted that Quercefit® significantly preserves eye and nose from discomforts and improves overall quality of life.9

EYE HEALTH
healthy ocular physiology in people experiencing allergic conjunctivitis, treated with continuous anti-allergy medications.10 Once again, the benefits of Quercefit® are tied to effective target delivery, provided by the unrivaled Phytosome™.

Furthermore, a series of case studies has highlighted that the oral administration of Quercefit® during topical antibiotic therapy on ocular tissues, damaged by mechanical, thermal or chemical trauma, can support faster restoration. The faster the better, when it comes to eye health.4

PHYSICAL PERFORMANCE
In triathlon athletes using Quercefit®, study have pointed out an optimization of training and performance and a leveling in oxidative stress. Quercefit® is the right partner to support optimal physical performance and prompt recovery.11

Phytosome™

Find out how Quercefit®
is one step beyond

Like it does for many other botanical extracts, the Phytosome™ delivery system transforms quercetin’s potential into real advantages, improving bioabsorption up to 20-fold, compared to the barely bioabsorbable natural form.3

The pioneering Phytosome™ technology, specifically intended to facilitate the dissolution profile and pharmacokinetics of botanical extracts, makes Quercefit® stand out.

That’s why Quercefit® contributes to overall wellbeing in many ways. Better performance, faster recovery.3

Find out more on Phytosome™

See through science

Bibliography
1 Di Pierro F. et al.; Int J Gen Med 14 (2021):2807-2816.
2 Di Pierro F. er al; Frontiers in Pharmacology (2023).
3Riva A. et al.; Eur J Drug Metab Pharmacokinet (2018).
4Mazzolani et al.; International Journal of Case Studies in Clinical Research (2022); Volume 6 Issue 3: 10-19.
5Liu, Chan-Min, et al.; Biochimica et Biophysica Acta (BBA)-General Subjects (2012); 1820.10: 1693-1703.
6Mlcek, Jiri, et al.; Molecules (2016); 21.5: 623.
7Rondanelli M. et al.; Life (2022).
8Cesarone, M. R., et al.; Minerva medica (2019).
9 Yamada, S. et al. European review for medical and pharmacological sciences (2022) 4331–4345.
10 Mazzolani et al.; Austin of allergy (2022).
11Riva A. et al.; Minerva Medica (2018); 109(4): 285-9.

QUERCEFIT® at a glance

Why choose Quercefit®?

01.

Based on Phytosome™, a natural and food-grade delivery system.

02.

Optimizes quercetin bioabsorption with dose linearity, proven to be up to 20-fold more bioavailable and effective at lower dosages, preserving its natural ingredient profile.

03.

Interactions with some common pharmacological therapies are undergoing further scrutiny, but present studies suggest no significant effects.

04.

Supports optimal physical performance and prompt recovery.

05.

Provides the benefits of traditional quercetin in respiratory health.

06.

Shows evidence of activity in conditions characterized by abnormal oxidative stress and immune responses.

07.

Easy to formulate stand-alone, easy to combine with multi-component formulations and versatile in terms of formulation options.

08.

Some studies have shown a possible positive protective effect on subjects exposed to viral load (i.e, Covid-19).

09.

Promotes faster eye wellbeing restoration.

10.

Has a pleiotropic antioxidant effect.

11.

It can be an aid fighting allergy related disturbs, also at ocular level.

Technical Data

Common Name

Quercefit® - Quercetin Phytosome™

Botanical Origin

Sophora japonica L.

Type

Extract

Plant source

Flower buds

-

Health benefit

Antioxidant activity, Eye wellbeing restoration, Immunity, Physical performance, Support in healing corneal and conjunctival trauma, Wellbeing optimization in allergy prone

Patent & Trademark

Quercefit® is patented.

Quercefit is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject Indena’s authorization and to the acceptance of the terms and conditions set out in the Trademark Usage Guidelines downloadable HERE.

Specifications

High quercetin bioabsorption, up to 20 times higher

Recommended dose and use

250 mg once or twice a day. Quercefit® may be used in a variety of supplement formulations.

Assay

≥34.0% ≤42.0% of quercetin by HPLC

Broad category

Respiratory Health, Sports nutrition, Eye health, Allergies

These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.

QUERCEFIT® documents

Quercefit™: effective for respiratory health, when allergies are rife

Indena presents its unique Phytosome formulation of quercetin derived from Sophora japonica L. The respiratory area is where its health benefits have been recently explored. 2 human studies showed very interesting results in maintaining wellbeing by sensitive or intolerant subjects.

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