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Opextan®

Opextan®

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Peer-reviewed science on Opextan®

Control of the oxidative stress4

Opextan® can effectively promote skin health by controlling oxidative stress.
Applied topically in a group of volunteers asked to apply Opextan® formulation and another formulation on their face and then wait for 3 hours and 20 minutes of sunlight irradiation, Opextan® decreases significantly sebum fluorescence of the administrated area (-27.1%), a direct measurement of lipid peroxidation.

Protection for skin4

Opextan® exerts a protective effect of on sensitive skin to ultraviolet (UV) irradiation. 13 male subjects with high sensitivity to UV light are selected and administrated orally with either a dose of 160 mg/day of Opextan® or not. The subjects are then irradiated with increasing doses of UV light in the dorsal area and minimal erythemal dose (MED) is evaluated. The results show a 16.45% result of MED after the administration compared to baseline.

opextan-01

Figure 1: Minimal erythemal dose (J/cm2) variation before and after Opextan®administration.

Supporting a healthy blood glucose level3

Olive pulp extract is also effective in maintaining blood glucose levels at a physiological level: after 12 weeks of olive extract administration on 15 subjects with glucose tolerance challenges, a significant optimization in fasting glucose levels is observed.

BIBLIOGRAPHY
1Obied H.K., et al., Chem Res Toxicol Jan 22(1): 227-34 (2009).
2Maramaldi G., et al., Cosmetic Technology 9 (5), 9-13 (2006).
3Keiko Suzuki et al., Off. J. of Japan Soc. Of Ningen Dock 25:825-830 (2011).
4Cristoni et al. Olive Fruit Extracts for Skin Health. Nutritional Cosmetics, 233–244, (2009).

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