健全な炎症反応
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カスペローム®
ボスウェリア フィトソーム®
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概要
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Thanks to its full spectrum of Boswellia serrata gum resin acids, captured and preserved through Indena Phytosome™ technology and precise standardization, Casperome® represents a scientifically validated solution to support body function for comprehensive well-being during the life course.
Moreover, thanks to its exclusive Indena Phytosome™ formulation, Casperome® shows an optimized distribution since the first administration.
MUSKOSKELETAL HEALTH
Casperome® supports musculoskeletal health reducing stress and inflammatory status of joints and muscles of actual athletes. An example? It can help to heal from ankle sprains and relieve knee joint from stress.5,6
GUT HEALTH
Recent human studies have focused on the possible role of Casperome® in the management of subjects with gastrointestinal issues like acute diarrhea and new human evidence confirms the benefits in reducing discomforts and promoting a faster normalization of the gut health status.4,7,8,9
RESPIRATORY HEALTH
An add-on administration of Casperome® is beneficial for people with asthma as it helps reduce the need for inhalation therapy with ICS + LABA.10
Casperome®がもたらす作用
Casperome® has been shown to:
• support the management of gut discomforts;
• support the management of airways discomforts during allergy season;
• support the management of joints discomforts, helpiung full functionality and recovery in sports.
Casperome® formulation maximizes the delivery of the whole bouquet of boswellic acids, that is the triterpenoic acids of Boswellia serrata endowed with healthy inflammatory support activity via backed-up mechanisms:
• inhibition of cathepsin G (catG), a protease enzyme which can regulate immune reaction and inflammatory response by modifying chemokines, cytokines, and cell surface receptors, and activate some lymphocytes;
• inhibition of cytokines involved in inflammatory process, such as TH1, t TNF-α and interleukins (IL-1β);
• inhibition of enzymes crucial for modulation of inflammatory response, such as microsomal prostaglandin E synthase (mPGES)-1, involved in prostaglandins synthesis;
• inhibition of the synthesis of 5-lipoxygenase (5-LO), enzyme involved in synthesis of leukotrienes.
UNIQUENESS
カスペローム®がいかに 一歩先を進んでいるかを明らかにする
• Casperome® is a botanical ingredient with unique composition and formulation:
- It contains not only KBA and AKBA, but the whole bouquet of boswellic acids
- It closely matches the composition profile of B. serrata resin
• Human tested formulation able to enhance and accelerate the delivery of terpenoic acids compared to unformulated extract
- Casperome® is the only ingredient on the market with a PK study on 6 boswellic acids;
- Boswellic acids are delivered, in average, 3 times more efficiently than with the unformulated extract;
- Peak concentrations of boswellic acids are reached faster than with the unformulated extract.
Casperome® is the only Boswellia extract with human studies on the management of airways discomforts during allergy season and on gut health.
The uniqueness of Casperome® is rooted in its Phytosome® strategy. The Phytosome® delivery system can optimize the biological absorption of boswellic acids normally poorly soluble delivering a specific phytochemical profile.
Pioneering Phytosome® formulation is specifically intended to facilitate dissolution profile and botanical extracts, making Casperome® so distinctive.
The bioabsorption of boswellic acids from Casperome® is greatly optimized both at plasma and tissue levels2 .
PHYTOSOMEについてもっと知る
科学を通して見る
参考文献目録
1. Riva A. et al, Phytomedicine 2016, 25, 1375-1382
2. Pellegrin L. et al., Eur Rev Med Pharmacol Sci. 2016, 20, 2695-2700
3. Belcaro, G. et al., Eur Rev Med Pharmacol Sci. 2017, 21, 2249-2254.
4. Riva A. et al, Minerva Gastroenterologica e Dietologica 2019, 65(1), 30-5
5. Ferrara, T. et al., Eur Rev Med Pharmacol Sci 2015, 20(19), 3757-3762.
6. Franceschi, F. et al., Eur Rev Med Pharmacol Sci 2016, 20(19), 4156-4161.
7. Fergalli, B., et al., Eur Rev Med Pharmacol Sci 2016, 20(19), 4726-4732.
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HEALTH STORIES / 23 10月 25
3.04
一目でわかるカスペローム®
カスペローム®を選ぶ理由
01.
ボスウェル酸で高度に標準化されており、生体吸収を最適化するためフィトソーム®送達システムを用いて処方されている。
02.
カスペローム®由来のボスウェル酸の生体吸収は、血漿中濃度と組織中濃度の両方で大幅に最適化される。
03.
薬物動態試験を含む、10件を超えるヒト試験によって裏付けられている。
04.
筋骨格の健康、特に肘や腱の問題をサポートできる。
Health Need
Chronic ache relief
Aches and chronic discomfort not only wear down the body, but can quickly affect quality of life. Our plant-based solutions work in tune with the body’s natural mechanisms to support healthy inflammatory response, calm physiological stress signals, and promote lasting relief.
Health Need
Weight loss companions
GLP-1 agonists are reshaping weight management – but not without challenges. Our botanical ingredients are designed to accompany the weight loss journey before, during, and after treatment, helping to counter side effects and support metabolic balance.
技術データ
一般名
カスペローム®－ボスウェリアフィトソーム®
基原植物
Boswellia serrata Roxb. ex Colebr. - Resin
種類
エキス
植物部位
樹脂
健康上の効能
呼吸器の健康, 消化器の健康, 炎症反応を正常に, 筋骨格系の健康, 関節の健康, Body function
商標
CasperomeカスペロームはIndena S.p.Aの商標です。
規格
Standardized to contain ≥25% of triterpenoid acids
推奨用量および用法
1日250～500 mg。カスペローム® は黄色の粉末で、さまざまな栄養補助食品に使用することができます。
アッセイ
ボスウェル酸25.0%以上 (HPLC)
広義のカテゴリー
健全な炎症反応、関節と腸の健康, Healthy aging
これらの記述は、お客様の国の法規制やReg. EC n.1924/2006に準拠していない可能性があり、米国食品医薬品局による評価を受けていません。本製品は、いかなる疾患の診断、治療、治癒または予防を目的としたものではありません。本成分を含有する最終製品の販売業者は、適用される法的枠組みの遵守を保証する責任を負っています。
カスペローム®文書
